European Union foreign policy chief Catherine Ashton delivers a statement during a ceremony at the United Nations in GenevaWith the aid of Parisa Hafezi and Justyna Pawlak GENEVA (Reuters) – Iran and six world powers clinched a deal on Sunday curbing the Iranian nuclear application in trade for initial sanctions reduction, signaling the beginning of a game-changing rapprochement that would scale back the danger of a much broader Middle East war. Aimed at easing a protracted festering standoff, the intervening time % between Iran and the US, France, Germany, Britain, China and Russia received the critical endorsement of Iranian clerical Supreme Leader Ayatollah Ali Khamenei. U.S. President Barack Obama mentioned the deal struck after marathon, tortuous and politically charged negotiations cut off Tehran's possible routes to a nuclear bomb. However Israel, Iran's arch-enemy, denounced the agreement as an "historic mistake".